CCBB Publications 2021 Onwards

  • Shared and Compartment-Specific Processes in Nucleus Pulposus and Annulus Fibrosus During Intervertebral Disc Degeneration: Swahn H, Mertens J, Olmer M, Myers K, Mondala TS, Natarajan P, Head SR, Alvarez-Garcia O, Lotz MK. Adv Sci (Weinh) 2024 May;11(17):e2309032. Epub 2024 Feb 25.PMID: 38403470; PMCID: PMC11077672; doi: 10.1002/advs.202309032

  • Transcriptomic analyses of joint tissues during osteoarthritis development in a rat model reveal dysregulated mechanotransduction and extracellular matrix pathways Hu Y, Li K, Swahn H, Ordoukhanian P, Head SR, Natarajan P, Woods AK, Joseph SB, Johnson KA, Lotz MK. Osteoarthritis Cartilage. 2023 Feb;31(2):199-212. doi:10.1016/j.joca.2022.10.003. Epub 2022 Oct 28. PMID: 36354073

  • Human-specific duplicate CHRFAM7A gene is associated with more severe osteoarthritis and amplifies pain behaviours: Courties A, Olmer M, Myers K, Ordoukhanian P, Head SR, Natarajan P, Berenbaum F, Sellam J, Lotz MK. Ann Rheum Dis. 2023 May;82(5):710-718. doi: 10.1136/ard-2022-223470. Epub 2023 Jan 10. PMID: 36627169 PMCID: PMC10101906 (available on 2024-05-01).

  • Senescent cell population with ZEB1 transcription factor as its main regulator promotes osteoarthritis in cartilage and meniscus: Swahn H, Li K, Duffy T, Olmer M, D’Lima DD, Mondala TS, Natarajan P, Head SR, Lotz MK. Ann Rheum Dis. 2023 Mar;82(3):403-415. doi: 10.1136/ard-2022-223227. Epub 2022 Dec 23. PMID: 36564153 PMCID: PMC10076001

  • Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis: Kawata M, Teramura T, Ordoukhanian P, Head SR, Natarajan P, Sundaresan A, Olmer M, Asahara H, Lotz MK. Ann Rheum Dis. 2022 May 9:annrheumdis-2021-221867. doi: 10.1136/annrheumdis-2021-221867. Online ahead of print. PMID: 35534137 DOI: 10.1136/annrheumdis-2021-221867

  • Maturation Delay of Human GABAergic Neurogenesis in Fragile X Syndrome Pluripotent Stem Cells: Ai Zhang, Irina Sokolova, Alain Domissy, Joshua Davis, Lee Rao, Kagistia Hana Utami, Yanling Wang, Randi J Hagerman, Mahmoud A Pouladi, Pietro Sanna, Michael J Boland, Jeanne F Loring. Stem Cells Translational Medicine, Volume 11, Issue 6, June 2022, Pages 613–629, doi.org/10.1093/stcltm/szac022

  • Ethanol withdrawal-induced adaptations in prefrontal corticotropin releasing factor receptor 1-expressing neurons regulate anxiety and conditioned rewarding effects of ethanol: Patel RR, Wolfe SA, Borgonetti V, Gandhi PJ, Rodriguez L, Snyder AE, D’Ambrosio S, Bajo M, Domissy A, Head S, Contet C, Dayne Mayfield R, Roberts AJ, Roberto M. Mol Psychiatry (2022). doi.org/10.1038/s41380-022-01642-3.

  • A non-synonymous SNP in SIRT6 predicts neurological severity in Friedreich ataxia: Layne N Rodden, Christian Rummey, Yi Na Dong, Sarah Lagedrost, Sean Regner, Alicia Brocht, Khalaf Bushara, Martin B Delatycki, Christopher M Gomez, Katherine Mathews, Sarah Murray, Susan L Perlman, Bernard Ravina, S H Subramony, George Wilmot, Theresa Zesiewicz, Alessandra Bolotta, Alain Domissy, Christine Jespersen, Baohu Ji, Elisabetta Soragni, Joel M. Gottesfeld and David R Lynch; Frontiers in Molecular Biosciences (2022) Pending

  • Integrative scRNA-seq analyses of human articular cartilage and meniscus reveal a pathogenic, senescent subpopulation that is expanded in OA, shared between both tissues, and has critical roles in extracellular matrix properties and tenascin signaling: Hannah Swahn, Tomas Duffy, Kun Li, Tony Mondala, Padmaja Natarajan, Steven R. Head and Martin K. Lotz; An abstract submitted to OARSI 2022

List of publications that acknowledged CCBB (2021 Onwards)

  • Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors: Gavin AL, Huang D, Blane TR, Thinnes TC, Murakami Y, Fukui R, Miyake K, Nemazee D. Nat Commun. 2021 Oct 7;12(1):5874. doi: 10.1038/s41467-021-26150-w. PMID: 34620855

  • Regulation of ex-translational activities is the primary function of the multi-tRNA synthetase complex: Cui H, Kapur M, Diedrich JK, Yates JR, Ackerman SL, Schimmel P. Nucleic Acids Res. 2021 Apr 19;49(7):3603-3616. doi: 10.1093/nar/gkaa1183. PMID: 33341895